PMLE can appear on any part of your body exposed to UV light, although it rarely appears on your face. It is sometimes referred to as "sun poisoning" or "sun allergy". doi:10.1016/j.jaad.2009.01.041. 2. Exposure to sunlight in spring or summer results in an irritable rash that resolves within a few days, providing further exposure is avoided. Phototoxic reactions Patterson JW. Advertising revenue supports our not-for-profit mission. Skin diseases due to physical and chemical causes", https://en.wikipedia.org/w/index.php?title=Polymorphous_light_eruption&oldid=1127125983, Skin conditions resulting from physical factors, Pages containing links to subscription-only content, Creative Commons Attribution-ShareAlike License 3.0, Shortly after sun exposure in people younger than age 30-years, This page was last edited on 13 December 2022, at 01:14. PLE can look like other skin conditions, some of which require prompt treatment. Theories must account for increased prevalence in women and for the hardening effect of on-going exposure to ultraviolet radiation. Four times more common in women than men. For polymorphous light eruption, some basic questions to ask your health care provider include: Your health care provider will ask you a number of questions about your symptoms and your medical history, such as: Avoid sun exposure whenever possible. doi:10.1016/j.det.2014.03.012. It looks like reddened skin with raised red spots or small blisters. If in doubt, call a doctor. Cleveland Clinic is a non-profit academic medical center. It resolves without scarring. The eruption appears first on limited areas, but becomes more extensive during subsequent summers. American Melanoma Foundation. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. It typically comes back each year when a person begins to have more sun on their skin. A 2014 study suggests that nutrition may also play a role in how sensitive a persons skin is to sun exposure. Dermatoses resulting from physical factors", "Photodermatoses: diagnosis and treatment", "Polymorphous light eruption - Symptoms, diagnosis and treatment | BMJ Best Practice", "Polymorphic light eruption | DermNet New Zealand", "CD 11b + cells markedly express the itch cytokine interleukin31 in polymorphic light eruption", "Polymorphic Light Eruption. Author: A/Prof Patrick Emanuel, Dermatopathologist, Auckland, New Zealand, 2013. Accessed Nov. 12, 2021. In up to 50% of cases, people with PLE have family members who also have the condition. Polymorphic light eruption. It is not always possible to completely prevent PLE in people who are prone to it. It also occurs in some patients treated for inflammatory skin diseases with phototherapy, when it may appear on the trunk and proximal limbs. Polymorphous light eruption - Diagnosis and treatment - Mayo Clinic UV-A is a major constituent of sunlight, can pass through glass, is relatively resistant to sunscreen and can cause light eruption without sunburn. Photochemical [PubMed PMID: 22961505], Richards HL,Ling TC,Evangelou G,Brooke RC,Fortune DG,Rhodes LE, Evidence of high levels of anxiety and depression in polymorphic light eruption and their association with clinical and demographic variables. A PLE rash can look similar to other skin rashes, so it is important to get a diagnosis from a doctor. Your health care provider might have you undergo laboratory tests in order to confirm a diagnosis or rule out other conditions. Language links are at the top of the page across from the title. Women between 20 and 40 with pale skin are the most affected, but anyone can have PMLE. Can diet help improve depression symptoms? [15], Oxidative stress and the modification of the redox status of the skin has been implicated in the expression of PLE. : Clinical Dermatology. 1986;3(5):298302. It is rare for people who get sunlight exposure year-round to have PLE. arrow-right-small-blue Polymorphous light eruption - Symptoms and causes - Mayo Clinic Its not as common, but you might have additional symptoms, like: Polymorphic means many forms, and PMLE can look different for different people. Affected individuals may experience it every time they go outdoors, or only occasionally. [5], Photosensitivity is also found in some of the porphyrias. In northern Europe, it may affect 2040% of women holidaying in the Mediterranean area, whereas in Australasian areas it is estimated to only affect between 15% of people. Up to 20% of people live with this problem. If PLE symptoms are mild, people may be able to manage the condition at home. DermNet provides Google Translate, a free machine translation service. arrow-right-small-blue Using high SPF, broad-spectrum sunscreen, and wearing protective clothing helps minimize UV light exposure. Polymorphic light eruption pathology. In: Nelson Textbook of Pediatrics. [6] It is thought to be due to a type IV delayed-type hypersensitivity to an allergen produced in the body following sunlight exposure,[12] in a genetically susceptible person. Idiopathic photodermatosis; Immunomediated photodermatosis; Minimal erythema dose; Photoprovocation tests; Phototests; Polymorphous light eruption; UV light. [4][8], PLE is also defined as an idiopathic primary photodermatosis,[9] in which the photosensitizer is unknown. Sunscreens. PLE causes small bumps or raised plaques on the skin. [3] The bumps may become small blisters or plaques and may appear bloody,[3]often healing with minimal scarring. Smooth red-topped small papules which merge into plaques, small fluid-filled blisters (papulovesicles)[2] and less commonly target-shaped lesions which look like erythema multiforme may be visible. It occurs most often on areas of skin that haven't seen the sun for a while - it is more common on the arms and the . 2014;32(3):315-viii. Recognizing and preventing sun allergies - Harvard Health [1] It generally appears 30 minutes to a few hours after sun exposure and may last between one and 14 days. There is no cure for PLE, but the condition often gets better on its own in a few days. Kittler H, Hnigsmann H, Tanew A: Antinuclear antibodies in patients with polymorphic light eruption: a long-term follow-up study. PMLE may be lifelong although 60% of people see improvement or resolution over 15 years and 75% of people in 30 years. Actas dermo-sifiliograficas. Polymorphous light eruption is typically diagnosed with a thorough health history and skin examination. Polymorphous light eruption (PLE) is the commonest immuno-mediated photodermatosis. It most often (about 75% of cases) begins in females aged 20 to 40 years but may start in childhood or later in life. Last reviewed by a Cleveland Clinic medical professional on 02/20/2023. She remembers having had the same problems last year. These changes are thought to restore the skins normal immunosuppressive response to UV light and hence reducing or resolving PMLE over time. The lesions occurred on the third day of her spring break vacation by the sea. An examination of the skin to detect the rash is made, however, up to 40% have false negative responses. It is also known as polymorphous light eruption, sun allergy, sun poisoning, prurigo aestivalis, summer eruption/prurigo, or eczema solare. National Library of Medicine Bookshelf Polycystic Ovary Syndrome (PCOS) Polycystic ovary syndrome, or PCOS, is a set of symptoms related to a hormonal imbalance that can affect women and girls of reproductive age. Polymorphous light eruption (PLE) is a common skin rash that occurs due to sunlight exposure. https://www.aad.org/media/stats-sunscreen. [1], The prevalence of polymorphic light eruption varies worldwide. Hematoxylin-eosin staining shows subepidermal edema and a mixed, predominantly lymphoid perivascular infiltrate in the superficial and deep dermis. An itchy rash will appear on areas that were newly exposed to the light, including: The rash usually doesnt affect the face. Specialized centers may undertake photoprovocation testing in late winter, to determine inciting wavelengths. This does not cause a problem in unaffected individuals because of UV-induced suppression. The following factors must be considered when determining pathogenesis and when implementing protective measures: UV radiation usually creates an immunosuppressive response in the skin, however, patients with PMLE may have a reduction in this normal response. Histology of PMLE. INTRODUCTION. In short, jock itch can spread between, Keloids can appear on your ear in response to any type of wound, including a piercing. Exposure to sunlight in spring or summer results in an irritable rash that resolves within a few days, providing further exposure is avoided. doi: 10.1016/j.jaad.2007.04.035. It is more common in patients who receive only intermittent sun exposure and typically consists of crops of papules, vesicles or plaques. Bethesda, MD 20894, Web Policies PLE is a relatively common skin disorder that is not easy to diagnose or manage. J Am Acad Dermatol. The best way to address PMLE is to avoid direct sun during the strongest parts of the day, wear appropriate sunscreen, and wear clothing that covers your skin. Learning Point. - "Polymorphous light eruption: clinic aspects and pathogenesis." HHS Vulnerability Disclosure, Help 2018 [PubMed PMID: 30250845], Gruber-Wackernagel A,Hofer A,Legat F,Wolf P, Frequency of occurrence of polymorphic light eruption in patients treated with photohardening and patients treated with phototherapy for other diseases. Careers. UVA causes up to 9 in 10 cases of polymorphous light eruption. A study across Europe found that PMLE affects as much as 18 percent of the population there. Possible complications of polymorphous light eruption. Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosis occurring in spring and early summer. If your symptoms are severe, your health care provider may prescribe anti-itch medicine (a corticosteroid cream or pill). It affects all skin types but is more common in lighter skin especially Fitzpatrick skin phototype 1, than in darker skins. 2008 Aug; [PubMed PMID: 18510674], Papular polymorphic light eruption on lower legs in female. Polymorphous light eruption is a rash caused by sun exposure in people who have developed sensitivity to sunlight. 8600 Rockville Pike Photohardening of polymorphic light eruption patients decreases baseline epidermal Langerhans cell density while increasing mast cell numbers in the papillary dermis. It often reduces in severity over time and eventually resolves with a lower prevalence in older people. Despite the fact that polymorphous light eruption (PLE) is the most common photodermatosis, affecting 15% of healthy people in the UK, its pathogeny remains unclear. Other light eruptions and eczematous reactions Photoallergic reactions and contact dermatitis can show a dense lymphocytic infiltrate to resemble PMLE. PLE is considered as a delayed hypersensitivity response to newly UV induced, but still unidentified, antigen(s). All rights reserved. 2014 Jul; [PubMed PMID: 24891050], Combalia A,Fernndez-Sartorio C,Fust X,Morgado-Carrasco D,Podlipnik S,Aguilera P, Successful Short Desensitization Treatment Protocol with Narrowband UVB Phototherapy (TL-01) in Polymorphic Light Eruption. It occurs after solar or artificial UV-light exposure and affects only the sun-exposed areas with preference of the V-area of the chest, of arms and forearms, legs, upper part of the back, and rarely the face.
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